Male participants and those with normal cognition had higher odds of being in the increaser group, regardless of stroke severity. The increaser group demonstrated a significant increase in physical activity level (mean difference, 0.27 linear slope β 1 = 0.46 P < .001) and sustained it at light intensity from 1 week to 6 months, whereas the decreaser group showed a decline in physical activity and eventually became inactive (mean difference, −0.26 linear slope β 1 = 1.81 P < .001). Results Of the 1367 included participants (median age, 72 years years 844 males ), 2 distinct trajectory groups were identified: increaser (n = 720 ) and decreaser (647 ). The secondary outcome was the functional recovery at 6 months after stroke, which was assessed using the modified Rankin Scale. Main Outcomes and Measures The primary outcomes were the distinct physical activity trajectories over time, which were identified using group-based trajectory modeling. Association of the distinct trajectories with functional recovery was assessed in multivariable logistic regression. Multiple factors associated with physical activity trajectories were investigated. Data analyses were performed between August 15 and October 28, 2022.Įxposures Physical activity was assessed at 1 week, 1 month, 3 months, and 6 months. Participants who withdrew or were lost to follow-up were excluded from the longitudinal analysis. Adult participants (aged >18 years) were recruited between 2 and 15 days after stroke onset and followed up for 6 months. Objective To assess the level of physical activity in the first 6 months after stroke among individuals with similar physical activity patterns over time and to investigate the association between physical activity trajectories and functional recovery at 6 months after stroke.ĭesign, Setting, and Participants This cohort study obtained data from the Efficacy of Fluoxetine–a Randomized Controlled Trial in Stroke, which was conducted in 35 stroke and rehabilitation centers across Sweden from October 2014 to June 2019. Importance The optimum level and timing of poststroke physical activity interventions to enhance functional recovery remain unclear. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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